March 17, 2026 at 12:55 pm

Scientists Finally Understand How Snakes Can Go For A Year Without Food, As They Sit Tight And Wait For A Meal To Appear Before Them

by Kyra Piperides

A close-up of the face of a python

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Love them or hate them, there’s no doubt that snakes are… unusual creatures.

From the way they move to the way they smell with their tongues and their unnerving ability to unhinge their jaws, there’s no denying that this predator has evolved in quite significant ways.

And sure it’s a cartoon trope, but the fact that you can see a snake’s big meal moving through its body is, perhaps, a big part of the reason that these reptiles are feared by many.

There’s no two ways about it. Snakes are weird creatures – and wonderful in many ways, too.

A diamond back rattlesnake

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If there’s one thing you might not know about snakes?

Sure we think of them as menacing carnivores, coiled up somewhere poised and ready to strike. But actually, these cold blooded creatures can actually live for months or even years without eating.

How? Well, this has been a mystery to scientists for quite some time. But thanks to researchers at the University of Porto and the University of Copenhagen (in Portugal and Denmark, respectively), we now have an answer.

In their study, which was recently published in the journal Open Biology, one fascinating aspect of snakes’ biology makes these big-eating limbless vertebrates also capable of eating very little at all.

A rattlesnake in its natural habitat

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Why do we, as humans, know to eat? Well, because our stomach produces a hormone called ghrelin, which tells your brain that you need to refuel. Even though this hormone is produced throughout the animal kingdom, the researchers discovered that snakes (among other reptiles) don’t usually produce ghrelin at all.

Moreover, snakes are lacking an enzyme known as MBOAT4 (membrane bound O-acyltransferase domain containing 4), which activates ghrelin.

Why? Well it’s likely an adaptation resulting from the way that snakes have evolved. After all, for a snake there is no knowing when prey will arrive: instead of hunting for food like mammals do, snakes merely wait it out.

Humans would be disadvantaged in this method, since ghrelin would be encouraging the body to burn fat while searching for food; snakes, instead, have a slowed metabolic rate as they wait for their next meal to appear – for hours, months, even years.

Only then, do they strike.

If you found that story interesting, learn more about why people often wake up around 3 AM and keep doing it for life.

Kyra Piperides, PhD | Contributing Science Writer

Dr. Kyra Piperides is a contributing writer for TwistedSifter, specializing in Science & Discovery. Holding a PhD in English with a dedicated focus on the intersections of science, politics, and literature, she brings over 12 years of professional writing and editorial expertise to her reporting.

Kyra possesses a highly authoritative background in academic publishing, having served as the editor of an academic journal for three years. She is also the published author of two books and numerous research-driven articles. At TwistedSifter, she leverages her rigorous academic background to translate complex scientific concepts, global tech innovations, and environmental breakthroughs into highly engaging, accessible narratives for a mainstream audience.

Based in the UK, Kyra is an avid backpacker who spends her free time immersing herself in different cultures across distant shores—a passion that brings a rich, global perspective to her writing about Earth and nature.

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